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Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family

The alternative pathway is a continuously active surveillance arm of the complement system, and it can also enhance complement activation initiated by the classical and the lectin pathways. Various membrane-bound and plasma regulatory proteins control the activation of the potentially deleterious co...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sánchez-Corral, Pilar, Pouw, Richard B., López-Trascasa, Margarita, Józsi, Mihály
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052053/
https://ncbi.nlm.nih.gov/pubmed/30050540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01607
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