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Anti-factor H antibody affecting factor H cofactor activity in a patient with dense deposit disease

Complement alternative pathway dysregulation seems to be the pathophysiological basis of Dense Deposit Disease (DDD). Here, we describe a monoclonal anti-factor H (FH) autoantibody in a woman diagnosed with DDD with a monoclonal gammapathy. Enzyme-linked immunosorbent assays evidenced the presence o...

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Detalhes bibliográficos
Publicado no:Clin Kidney J
Main Authors: Nozal, Pilar, Strobel, Stefanie, Ibernon, Meritxell, López, Dolores, Sánchez-Corral, Pilar, Rodríguez de Córdoba, Santiago, Józsi, Mihály, López-Trascasa, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783207/
https://ncbi.nlm.nih.gov/pubmed/29497514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfs002
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