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C–C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products

C–C bond formations are frequently the key steps in cofactor and natural product biosynthesis. Historically, C–C bond formations were thought to proceed by two electron mechanisms, represented by Claisen condensation in fatty acids and polyketide biosynthesis. These types of mechanisms require activ...

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Bibliografske podrobnosti
izdano v:Nat Prod Rep
Main Authors: Yokoyama, Kenichi, Lilla, Edward A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051890/
https://ncbi.nlm.nih.gov/pubmed/29633774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8np00006a
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