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On statistical modeling of sequencing noise in high depth data to assess tumor evolution
One cause of cancer mortality is tumor evolution to therapy-resistant disease. First line therapy often targets the dominant clone, and drug resistance can emerge from preexisting clones that gain fitness through therapy-induced natural selection. Such mutations may be identified using targeted sequ...
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| Publicado no: | J Stat Phys |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051708/ https://ncbi.nlm.nih.gov/pubmed/30034030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10955-017-1945-1 |
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