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Poor Immunogenicity, Not Vaccine Strain Egg Adaptation, May Explain the Low H3N2 Influenza Vaccine Effectiveness in 2012–2013

BACKGROUND: Influenza vaccination aims to prevent infection by influenza virus and reduce associated morbidity and mortality; however, vaccine effectiveness (VE) can be modest, especially for subtype A(H3N2). Low VE has been attributed to mismatches between the vaccine and circulating influenza stra...

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Dades bibliogràfiques
Publicat a:Clin Infect Dis
Autors principals: Cobey, Sarah, Gouma, Sigrid, Parkhouse, Kaela, Chambers, Benjamin S, Ertl, Hildegund C, Schmader, Kenneth E, Halpin, Rebecca A, Lin, Xudong, Stockwell, Timothy B, Das, Suman R, Landon, Emily, Tesic, Vera, Youngster, Ilan, Pinsky, Benjamin A, Wentworth, David E, Hensley, Scott E, Grad, Yonatan H
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051447/
https://ncbi.nlm.nih.gov/pubmed/29471464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy097
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