Poor Immunogenicity, Not Vaccine Strain Egg Adaptation, May Explain the Low H3N2 Influenza Vaccine Effectiveness in 2012–2013

BACKGROUND: Influenza vaccination aims to prevent infection by influenza virus and reduce associated morbidity and mortality; however, vaccine effectiveness (VE) can be modest, especially for subtype A(H3N2). Low VE has been attributed to mismatches between the vaccine and circulating influenza stra...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Cobey, Sarah, Gouma, Sigrid, Parkhouse, Kaela, Chambers, Benjamin S, Ertl, Hildegund C, Schmader, Kenneth E, Halpin, Rebecca A, Lin, Xudong, Stockwell, Timothy B, Das, Suman R, Landon, Emily, Tesic, Vera, Youngster, Ilan, Pinsky, Benjamin A, Wentworth, David E, Hensley, Scott E, Grad, Yonatan H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Articles and Commentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051447/
https://ncbi.nlm.nih.gov/pubmed/29471464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy097
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