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Solubility Enhancement of Domperidone by Solvent Change In situ Micronization Technique

BACKGROUND: Domperidone (DOM), a dopamine receptor antagonist, is used as antiemetic for the treatment of gastroparesis, vomiting, and nausea. The low water solubility of DOM leads to a low dissolution rate and variable bioavailability. The aim of this study was to enhance the solubility of DOM by t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Adv Biomed Res
Egile Nagusiak: Enteshari, Saeede, Varshosaz, Jaleh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Medknow Publications & Media Pvt Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050975/
https://ncbi.nlm.nih.gov/pubmed/30069440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/abr.abr_219_17
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