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Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening

The primary cilium is an essential organelle mediating key signaling activities, such as sonic hedgehog signaling. The molecular composition of the ciliary compartment is distinct from that of the cytosol, with the transition zone (TZ) gated the ciliary base. The TZ is a packed and organized protein...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Weng, Rueyhung Roc, Yang, T. Tony, Huang, Chia-En, Chang, Chih-Wei, Wang, Won-Jing, Liao, Jung-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050714/
https://ncbi.nlm.nih.gov/pubmed/29866362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.04.051
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