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Toxicity and Pharmacokinetic Studies of Aerosolized Clinical Grade Azacitidine

Aerosolized clinical grade azacitidine (Aza) was tested for aerosol quality in vitro and pharmacokinetics and systemic and pulmonary toxicity in vivo in mice. The aerodynamic size range of the aerosol droplets favored the deposit of the drug to the human lower airways and the aerosol process did not...

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Bibliografiske detaljer
Udgivet i:Clin Lung Cancer
Main Authors: Qiu, Xuan, Liang, Yuanxin, Sellers, Rani S, Perez-Soler, Roman, Zou, Yiyu
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050589/
https://ncbi.nlm.nih.gov/pubmed/26531130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cllc.2015.09.005
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