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Unusual biaryl torsional strain promotes reactivity in Cu-catalyzed Sommelet–Hauser rearrangement

A Cu-catalyzed Sommelet–Hauser dearomatization of dihydrophenanthridine and diazo compounds is reported for the synthesis of spiro-indolines. A spiro-structure with adjacent quaternary and tertiary carbon centers was constructed in one step as a single isomer. Increasing steric hindrance by introduc...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Pan, Chongqing, Guo, Wenjing, Gu, Zhenhua
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050577/
https://ncbi.nlm.nih.gov/pubmed/30079198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01657g
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