Plasmatic Levels of IL-18, IP-10, and Activated CD8(+) T Cells Are Potential Biomarkers to Identify HIV-1 Elite Controllers With a True Functional Cure Profile

Elite controllers (ECs) are rare individuals able to naturally control HIV-1 replication below the detection limit of viral load (VL) commercial assays. It is unclear, however, whether ECs might be considered a natural model of a functional cure because some studies have noted CD4(+) T cell depletio...

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Vydáno v:Front Immunol
Hlavní autoři: Côrtes, Fernanda H., de Paula, Hury H. S., Bello, Gonzalo, Ribeiro-Alves, Marcelo, de Azevedo, Suwellen S. D., Caetano, Diogo G., Teixeira, Sylvia L. M., Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea G., Guimarães, Monick L., Morgado, Mariza G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050358/
https://ncbi.nlm.nih.gov/pubmed/30050532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01576
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