Proviral Quasispecies Diversity Is Not Associated With Virologic Breakthrough or CD4(+) T Cell Loss in HIV-1 Elite Controllers

Elite controllers (EC) are able to control HIV-1 replication to extremely low levels (<50 HIV-1 RNA copies/mL) in the absence of antiretroviral therapy. However, some EC experience CD4(+) T cell loss and/or lose their ability to control HIV-1 over the course of infection. High levels of HIV-1 env...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: de Azevedo, Suwellen S. D., Côrtes, Fernanda H., Delatorre, Edson, Ribeiro-Alves, Marcelo, Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea G., Morgado, Mariza G., Bello, Gonzalo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454058/
https://ncbi.nlm.nih.gov/pubmed/31001238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00673
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