A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling

Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially modulated are unknown. Here we show that the pos...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Parvatiyar, Kislay, Pindado, Jose, Dev, Anurupa, Aliyari, Saba Roghiyh, Zaver, Shivam A., Gerami, Hoda, Chapon, Maxime, Ghaffari, Amir A., Dhingra, Anant, Cheng, Genhong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050272/
https://ncbi.nlm.nih.gov/pubmed/30018345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05168-7
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