The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

Cell cycle progression in mammals is modulated by two ubiquitin ligase complexes, CRL4 and SCF, which facilitate degradation of chromatin substrates involved in the regulation of DNA replication. One member of the CRL4 complex, the WD-40 containing protein RepID (DCAF14/PHIP), selectively binds and...

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Udgivet i:Nat Commun
Main Authors: Jang, Sang-Min, Zhang, Ya, Utani, Koichi, Fu, Haiqing, Redon, Christophe E., Marks, Anna B., Smith, Owen K., Redmond, Catherine J., Baris, Adrian M., Tulchinsky, Danielle A., Aladjem, Mirit I.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050238/
https://ncbi.nlm.nih.gov/pubmed/30018425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05177-6
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