Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol

Pleiotrophin (PTN) and Midkine (MK) are neurotrophic factors that are upregulated in the prefrontal cortex after alcohol administration and have been shown to reduce ethanol drinking and reward. PTN and MK are the endogenous inhibitors of Receptor Protein Tyrosine Phosphatase (RPTP) β/ζ (a.k.a. PTPR...

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Publicado no:Neuropharmacology
Main Authors: Fernández-Calle, Rosalía, Vicente-Rodríguez, Marta, Pastor, Miryam, Gramage, Esther, Di Geronimo, Bruno, Zapico, José María, Coderch, Claire, Pérez-García, Carmen, Lasek, Amy W., de Pascual-Teresa, Beatriz, Ramos, Ana, Herradón, Gonzalo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050104/
https://ncbi.nlm.nih.gov/pubmed/29753117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.04.027
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