Cancer-associated fibroblasts drive glycolysis in a targetable signaling loop implicated in head and neck squamous cell carcinoma progression

Despite aggressive therapies, head and neck squamous cell carcinoma (HNSCC) is associated with a less than 50% 5-year survival rate. Late stage HNSCC frequently consists of up to 80% cancer-associated fibroblasts (CAF). We previously reported that CAF-secreted hepatocyte growth factor (HGF) facilita...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cancer Res
المؤلفون الرئيسيون: Kumar, Dhruv, New, Jacob, Vishwakarma, Vikalp, Joshi, Radhika, Enders, Jonathan, Lin, Fangchen, Dasari, Sumana, Gutierrez, Wade R, Leef, George, Ponnurangam, Sivapriya, Chavan, Hemantkumar, Ganaden, Lydia, Thornton, Mackenzie M., Dai, Hongying, Tawfik, Ossama, Straub, Jeffrey, Shnayder, Yelizaveta, Kakarala, Kiran, Tsue, Terance Ted, Girod, Douglas A., Van Houten, Bennett, Anant, Shrikant, Krishnamurthy, Partha, Thomas, Sufi Mary
التنسيق: Artigo
اللغة:Inglês
منشور في: 2018
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050074/
https://ncbi.nlm.nih.gov/pubmed/29769197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1076
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