Genome Editing and Induced Pluripotent Stem Cells in Cardiac Channelopathy

BACKGROUND: The long QT syndrome (LQTS) is an arrhythmogenic disorder of QT interval prolongation that predisposes patients to life-threatening ventricular arrhythmias such as Torsade de pointes (TdP) and sudden cardiac death (SCD). Clinical genetic testing has emerged as the standard of care to ide...

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Bibliografiske detaljer
Udgivet i:J Am Coll Cardiol
Main Authors: Garg, Priyanka, Oikonomopoulos, Angelos, Chen, Haodong, Li, Yingxin, Lam, Chi Keung, Sallam, Karim, Perez, Marco, Lux, Robert L., Sanguinetti, Michael C., Wu, Joseph C.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050025/
https://ncbi.nlm.nih.gov/pubmed/29957233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2018.04.041
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