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Detection of cooperatively bound transcription factor pairs using ChIP-seq peak intensities and expectation maximization
Transcription factors (TFs) often work cooperatively, where the binding of one TF to DNA enhances the binding affinity of a second TF to a nearby location. Such cooperative binding is important for activating gene expression from promoters and enhancers in both prokaryotic and eukaryotic cells. Exis...
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| Published in: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049898/ https://ncbi.nlm.nih.gov/pubmed/30016330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199771 |
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