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Detection of cooperatively bound transcription factor pairs using ChIP-seq peak intensities and expectation maximization

Transcription factors (TFs) often work cooperatively, where the binding of one TF to DNA enhances the binding affinity of a second TF to a nearby location. Such cooperative binding is important for activating gene expression from promoters and enhancers in both prokaryotic and eukaryotic cells. Exis...

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發表在:PLoS One
Main Authors: Datta, Vishaka, Siddharthan, Rahul, Krishna, Sandeep
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049898/
https://ncbi.nlm.nih.gov/pubmed/30016330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199771
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