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Inhibitory effect of vitamin C on intrinsic aging in human dermal fibroblasts and hairless mice
Vitamin C significantly reduced senescence-associated β-galactosidase (SA-β-gal) activity, with both the suppression of cell-cycle inhibitors (p53, p21, p16, and pRb) and stimulation of cell-cycle activators (E2F1 and E2F2). Vitamin C also effectively attenuated the hyperactivation of the phosphatid...
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| Publicado no: | Food Sci Biotechnol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049637/ https://ncbi.nlm.nih.gov/pubmed/30263780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10068-017-0252-6 |
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