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Piper retrofractum Vahl. Extract, as a PPARδ and AMPK Activator, Suppresses UVB-Induced Photoaging through Mitochondrial Biogenesis and MMPs Inhibition in Human Dermal Fibroblasts and Hairless Mice

Photoaging occurs by UVB-irradiation and involves production of reactive oxygen species (ROS) and overexpression of matrix metalloproteinases (MMPs), leading to extracellular matrix damage. Piper retrofractum Vahl. is used as a traditional medicine for antiflatulence, expectorant, sedative, and anti...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Yun, Jungon, Kim, Changhee, Kim, Mi-Bo, Hwang, Jae-Kwan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829337/
https://ncbi.nlm.nih.gov/pubmed/29619069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6172954
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