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High-yielding (18)F radiosynthesis of a novel oxytocin receptor tracer, a probe for nose-to-brain oxytocin uptake in vivo

A novel Al(18)F labelled peptide tracer for PET imaging of oxytocin receptor has been accessed through a high radiochemical yield approach. This tracer showed comparable affinity and higher selectivity and stability compared to oxytocin, and was used to demonstrate direct nose-to-brain uptake follow...

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Detaylı Bibliyografya
Yayımlandı:Chem Commun (Camb)
Asıl Yazarlar: Beard, Rhiannon, Singh, Nisha, Grundschober, Christophe, Gee, Antony D., Tate, Edward W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049614/
https://ncbi.nlm.nih.gov/pubmed/29974895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc01400k
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