Type I interferons instigate fetal demise after Zika virus infection

Zika virus (ZIKV) infection during pregnancy is associated with adverse fetal outcomes including microcephaly, growth restriction, and fetal demise. Type I interferons (IFNs) are essential for host resistance against ZIKV, and IFN-α/β receptor (IFNAR)-deficient mice are highly susceptible to ZIKV in...

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Bibliografiske detaljer
Udgivet i:Sci Immunol
Main Authors: Yockey, Laura J., Jurado, Kellie A., Arora, Nitin, Millet, Alon, Rakib, Tasfia, Milano, Kristin M., Hastings, Andrew K., Fikrig, Erol, Kong, Yong, Horvath, Tamas L., Weatherbee, Scott, Kliman, Harvey J., Coyne, Carolyn B., Iwasaki, Akiko
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049088/
https://ncbi.nlm.nih.gov/pubmed/29305462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao1680
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