Type I interferons instigate fetal demise after Zika virus infection

Zika virus (ZIKV) infection during pregnancy is associated with adverse fetal outcomes including microcephaly, growth restriction, and fetal demise. Type I interferons (IFNs) are essential for host resistance against ZIKV, and IFN-α/β receptor (IFNAR)-deficient mice are highly susceptible to ZIKV in...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Yockey, Laura J., Jurado, Kellie A., Arora, Nitin, Millet, Alon, Rakib, Tasfia, Milano, Kristin M., Hastings, Andrew K., Fikrig, Erol, Kong, Yong, Horvath, Tamas L., Weatherbee, Scott, Kliman, Harvey J., Coyne, Carolyn B., Iwasaki, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049088/
https://ncbi.nlm.nih.gov/pubmed/29305462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao1680
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