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Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP‐305, a novel farnesoid X receptor agonist

We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic resonance imaging with the type 1 collagen‐binding probe EP‐3533...

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Dades bibliogràfiques
Publicat a:Hepatol Commun
Autors principals: Erstad, Derek J., Farrar, Christian T., Ghoshal, Sarani, Masia, Ricard, Ferreira, Diego S., Chen, Yin‐Ching Iris, Choi, Ji‐Kyung, Wei, Lan, Waghorn, Phillip A., Rotile, Nicholas J., Tu, Chuantao, Graham‐O'Regan, Katherine A., Sojoodi, Mozhdeh, Li, Shen, Li, Yang, Wang, Guogiang, Corey, Kathleen E., Or, Yat Sun, Jiang, Lijuan, Tanabe, Kenneth K., Caravan, Peter, Fuchs, Bryan C.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049071/
https://ncbi.nlm.nih.gov/pubmed/30027140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1193
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