Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP‐305, a novel farnesoid X receptor agonist

We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic resonance imaging with the type 1 collagen‐binding probe EP‐3533...

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Publicado no:Hepatol Commun
Main Authors: Erstad, Derek J., Farrar, Christian T., Ghoshal, Sarani, Masia, Ricard, Ferreira, Diego S., Chen, Yin‐Ching Iris, Choi, Ji‐Kyung, Wei, Lan, Waghorn, Phillip A., Rotile, Nicholas J., Tu, Chuantao, Graham‐O'Regan, Katherine A., Sojoodi, Mozhdeh, Li, Shen, Li, Yang, Wang, Guogiang, Corey, Kathleen E., Or, Yat Sun, Jiang, Lijuan, Tanabe, Kenneth K., Caravan, Peter, Fuchs, Bryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049071/
https://ncbi.nlm.nih.gov/pubmed/30027140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1193
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