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Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy

Syngeneic, immunocompetent allograft tumor models recapitulate important aspects of the tumor microenvironment and have short tumor latency with predictable growth kinetics, making them useful for trialing novel therapeutics. Here, we describe surgical techniques for orthotopic and heterotopic pancr...

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Podrobná bibliografie
Vydáno v:Dis Model Mech
Hlavní autoři: Erstad, Derek J., Sojoodi, Mozhdeh, Taylor, Martin S., Ghoshal, Sarani, Razavi, Allen A., Graham-O'Regan, Katherine A., Bardeesy, Nabeel, Ferrone, Cristina R., Lanuti, Michael, Caravan, Peter, Tanabe, Kenneth K., Fuchs, Bryan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078400/
https://ncbi.nlm.nih.gov/pubmed/29903803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.034793
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