Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy

Syngeneic, immunocompetent allograft tumor models recapitulate important aspects of the tumor microenvironment and have short tumor latency with predictable growth kinetics, making them useful for trialing novel therapeutics. Here, we describe surgical techniques for orthotopic and heterotopic pancr...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Erstad, Derek J., Sojoodi, Mozhdeh, Taylor, Martin S., Ghoshal, Sarani, Razavi, Allen A., Graham-O'Regan, Katherine A., Bardeesy, Nabeel, Ferrone, Cristina R., Lanuti, Michael, Caravan, Peter, Tanabe, Kenneth K., Fuchs, Bryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078400/
https://ncbi.nlm.nih.gov/pubmed/29903803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.034793
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