Φορτώνει......
Diacylglycerol kinase ζ (DGKζ) and Casitas b-lineage proto-oncogene b–deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance
Targeting negative regulators downstream of the T cell receptor (TCR) represents a novel strategy to improve cancer immunotherapy. Two proteins that serve as critical inhibitory regulators downstream of the TCR are diacylglycerol kinase ζ (DGKζ), a regulator of Ras and PKC-θ signaling, and Casitas b...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Immunohorizons |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048965/ https://ncbi.nlm.nih.gov/pubmed/30027154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1700055 |
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