Germline and somatic variations influence the somatic mutational signatures of esophageal squamous cell carcinomas in a Chinese population

BACKGROUND: Esophageal squamous cell carcinomas (ESCC) is the fourth most lethal cancer in China. Previous studies reveal several highly conserved mutational processes in ESCC. However, it remains unclear what are the true regulators of the mutational processes. RESULTS: We analyzed the somatic muta...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Guo, Jintao, Huang, Jiankun, Zhou, Ying, Zhou, Yulin, Yu, Liying, Li, Huili, Hou, Lingyun, Zhu, Liuwei, Ge, Dandan, Zeng, Yuanyuan, Guleng, Bayasi, Li, Qiyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048762/
https://ncbi.nlm.nih.gov/pubmed/30012096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4906-4
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