Germline and somatic variations influence the somatic mutational signatures of esophageal squamous cell carcinomas in a Chinese population

BACKGROUND: Esophageal squamous cell carcinomas (ESCC) is the fourth most lethal cancer in China. Previous studies reveal several highly conserved mutational processes in ESCC. However, it remains unclear what are the true regulators of the mutational processes. RESULTS: We analyzed the somatic muta...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Guo, Jintao, Huang, Jiankun, Zhou, Ying, Zhou, Yulin, Yu, Liying, Li, Huili, Hou, Lingyun, Zhu, Liuwei, Ge, Dandan, Zeng, Yuanyuan, Guleng, Bayasi, Li, Qiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048762/
https://ncbi.nlm.nih.gov/pubmed/30012096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4906-4
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