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Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7

The La and the La-related protein (LARP) superfamily is a diverse class of RNA binding proteins involved in RNA processing, folding, and function. Larp7 binds to the abundant long noncoding 7SK RNA and is required for 7SK ribonucleoprotein (RNP) assembly and function. The 7SK RNP sequesters a pool o...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Eichhorn, Catherine D., Yang, Yuan, Repeta, Lucas, Feigon, Juli
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048529/
https://ncbi.nlm.nih.gov/pubmed/29946027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806276115
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