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O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2
Protein O-glycosylation by attachment of β-N-acetylglucosamine (GlcNAc) to the Ser or Thr residue is a major posttranslational glycosylation event and is often associated with protein folding, stability, and activity. The methylation of histone H3 at Lys-27 catalyzed by the methyltransferase EZH2 wa...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048490/ https://ncbi.nlm.nih.gov/pubmed/29941599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801850115 |
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