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O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2

Protein O-glycosylation by attachment of β-N-acetylglucosamine (GlcNAc) to the Ser or Thr residue is a major posttranslational glycosylation event and is often associated with protein folding, stability, and activity. The methylation of histone H3 at Lys-27 catalyzed by the methyltransferase EZH2 wa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Lo, Pei-Wen, Shie, Jiun-Jie, Chen, Chein-Hung, Wu, Chung-Yi, Hsu, Tsui-Ling, Wong, Chi-Huey
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048490/
https://ncbi.nlm.nih.gov/pubmed/29941599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801850115
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