O-GlcNAcylation regulates EZH2 protein stability and function

O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is the only known enzyme that catalyzes the O-GlcNAcylation of proteins at the Ser or Thr side chain hydroxyl group. OGT participates in transcriptional and epigenetic regulation, and dysregulation of OGT has been implicated in diseases such as...

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Bibliografiske detaljer
Main Authors: Chu, Chi-Shuen, Lo, Pei-Wen, Yeh, Yi-Hsien, Hsu, Pang-Hung, Peng, Shih-Huan, Teng, Yu-Ching, Kang, Ming-Lun, Wong, Chi-Huey, Juan, Li-Jung
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910655/
https://ncbi.nlm.nih.gov/pubmed/24474760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323226111
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