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Structure of the Lassa virus glycan shield provides a model for immunological resistance

Lassa virus is an Old World arenavirus endemic to West Africa that causes severe hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein complex (GPC) that extends from the virion envelope. The often inadequate antibody immune response elicited by both vaccine and natural inf...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Watanabe, Yasunori, Raghwani, Jayna, Allen, Joel D., Seabright, Gemma E., Li, Sai, Moser, Felipe, Huiskonen, Juha T., Strecker, Thomas, Bowden, Thomas A., Crispin, Max
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048489/
https://ncbi.nlm.nih.gov/pubmed/29941589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803990115
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