Structure of the Lassa virus glycan shield provides a model for immunological resistance

Lassa virus is an Old World arenavirus endemic to West Africa that causes severe hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein complex (GPC) that extends from the virion envelope. The often inadequate antibody immune response elicited by both vaccine and natural inf...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Watanabe, Yasunori, Raghwani, Jayna, Allen, Joel D., Seabright, Gemma E., Li, Sai, Moser, Felipe, Huiskonen, Juha T., Strecker, Thomas, Bowden, Thomas A., Crispin, Max
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048489/
https://ncbi.nlm.nih.gov/pubmed/29941589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803990115
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