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Structure of the Lassa virus glycan shield provides a model for immunological resistance
Lassa virus is an Old World arenavirus endemic to West Africa that causes severe hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein complex (GPC) that extends from the virion envelope. The often inadequate antibody immune response elicited by both vaccine and natural inf...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048489/ https://ncbi.nlm.nih.gov/pubmed/29941589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803990115 |
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