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Structure of the Lassa virus glycan shield provides a model for immunological resistance

Lassa virus is an Old World arenavirus endemic to West Africa that causes severe hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein complex (GPC) that extends from the virion envelope. The often inadequate antibody immune response elicited by both vaccine and natural inf...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Watanabe, Yasunori, Raghwani, Jayna, Allen, Joel D., Seabright, Gemma E., Li, Sai, Moser, Felipe, Huiskonen, Juha T., Strecker, Thomas, Bowden, Thomas A., Crispin, Max
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048489/
https://ncbi.nlm.nih.gov/pubmed/29941589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803990115
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