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Chronic renal artery insulin infusion increases mean arterial pressure in male Sprague-Dawley rats

Hyperinsulinemia has been hypothesized to cause hypertension in obesity, type 2 diabetes, and metabolic syndrome through a renal mechanism. However, it has been challenging to isolate renal mechanisms in chronic experimental models due, in part, to technical difficulties. In this study, we tested th...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Irsik, Debra L., Chen, Jian-Kang, Brands, Michael W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048445/
https://ncbi.nlm.nih.gov/pubmed/28971990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00374.2017
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