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Inhibition of microRNA-429 in the renal medulla increased salt sensitivity of blood pressure in Sprague Dawley rats
BACKGROUND: We have previously shown that high salt intake suppresses the expression of prolyl hydroxylase domain-containing protein 2 (PHD2), an enzyme promoting the degradation of hypoxia inducible factor (HIF)-1α, and increases HIF-1α along with its target genes in the renal medulla, which promot...
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| Publicado no: | J Hypertens |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837286/ https://ncbi.nlm.nih.gov/pubmed/28445205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001373 |
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