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Pregnancy-associated plasma protein a in cancer: expression, oncogenic functions and regulation

Pregnancy-associated plasma protein A (PAPPA) is a protease that plays important roles in pregnancy, but interestingly acts as an oncogene outside of pregnancy. This review summarizes the oncogenic roles of PAPPA, including its expression levels in multiple malignancies, regulatory and signaling int...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Guo, Yongchen, Bao, Yonghua, Guo, Dongli, Yang, Wancai
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048405/
https://ncbi.nlm.nih.gov/pubmed/30034934
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