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Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

Ferroptosis is a newly described form of regulated cell death, distinct from apoptosis, necroptosis and other forms of cell death. Ferroptosis is induced by disruption of glutathione synthesis or inhibition of glutathione peroxidase 4, exacerbated by iron, and prevented by radical scavengers such as...

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Bibliografski detalji
Izdano u:Front Neurosci
Glavni autori: Abdalkader, Moataz, Lampinen, Riikka, Kanninen, Katja M., Malm, Tarja M., Liddell, Jeffrey R.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048292/
https://ncbi.nlm.nih.gov/pubmed/30042655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00466
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