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Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway

Specific regions of the Alzheimer's disease (AD) brain are burdened with extracellular protein deposits, the accumulation of which is concomitant with a complex cascade of overlapping events. Many of these pathological processes produce oxidative stress. Under normal conditions, oxidative stres...

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Detalhes bibliográficos
Main Authors: Kanninen, Katja, White, Anthony R., Koistinaho, Jari, Malm, Tarja
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100734/
https://ncbi.nlm.nih.gov/pubmed/21629716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/985085
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