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The Role of Microglia in the Spread of Tau: Relevance for Tauopathies

Tauopathies are neurodegenerative diseases which course with the accumulation of Tau, mainly in neurons. In addition, Tau accumulates in a hyperphosphorylated and aggregated form. This protein is released into the extracellular space and spreads following a stereotypical pattern, inducing the develo...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Perea, Juan R., Llorens-Martín, María, Ávila, Jesús, Bolós, Marta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048186/
https://ncbi.nlm.nih.gov/pubmed/30042659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00172
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