A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

The recurrence of new human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the need for effective therapeutic countermeasures. Nonhuman primate models are considered the gold standard for preclinical evaluation of therapeutic countermeasures. However, MERS-CoV-induced s...

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Publicat a:Sci Rep
Autors principals: Cockrell, Adam S., Johnson, Joshua C., Moore, Ian N., Liu, David X., Bock, Kevin W., Douglas, Madeline G., Graham, Rachel L., Solomon, Jeffrey, Torzewski, Lisa, Bartos, Christopher, Hart, Randy, Baric, Ralph S., Johnson, Reed F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048037/
https://ncbi.nlm.nih.gov/pubmed/30013082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28900-1
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