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Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process

Matrix metalloproteinases (MMPs) are considered excellent targets for cancer therapy because of their important roles in multiple aspects of tumor growth and metastatic spread. However, not all MMPs, or even all activities of specific MMPs, promote cancer. Therefore, there is a need for highly speci...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Kuan-Hui E., Chen, Chuan, Lopez, Tyler, Radecki, Kelly C., Bustamante, Karissa, Lorenson, Mary Y., Ge, Xin, Walker, Ameae M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047671/
https://ncbi.nlm.nih.gov/pubmed/30034628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25654
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