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Mimicry of a β-Hairpin Turn by a Nonpeptidic Laterally Flexible Foldamer
The design and characterization of a proteomimetic foldamer that displays lateral flexibility endowed by intramolecular bifurcated hydrogen bonds is reported. The MAMBA scaffold, derived from meta-aminomethylbenzoic acid, adopts a serpentine conformation that mimics the side chain projection of all...
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| Publicado no: | Org Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6047514/ https://ncbi.nlm.nih.gov/pubmed/29897248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01463 |
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