Antiatherosclerotic Effects of 1-Methylnicotinamide in Apolipoprotein E/Low-Density Lipoprotein Receptor–Deficient Mice: A Comparison with Nicotinic Acid

1-Methylnicotinamide (MNA), the major endogenous metabolite of nicotinic acid (NicA), may partially contribute to the vasoprotective properties of NicA. Here we compared the antiatherosclerotic effects of MNA and NicA in apolipoprotein E (ApoE)/low-density lipoprotein receptor (LDLR)–deficient mice....

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Mateuszuk, Lukasz, Jasztal, Agnieszka, Maslak, Edyta, Gasior-Glogowska, Marlena, Baranska, Malgorzata, Sitek, Barbara, Kostogrys, Renata, Zakrzewska, Agnieszka, Kij, Agnieszka, Walczak, Maria, Chlopicki, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047228/
https://ncbi.nlm.nih.gov/pubmed/26631491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.228643
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