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Inhibition of Connexin Hemichannels by New Amphiphilic Aminoglycosides without Antibiotic Activity
[Image: see text] Connexins hemichannels (HCs) from adjacent cells form gap junctional channels that mediate cell-to-cell communication. Abnormal opening of “free” undocked HCs can produce cell damage and participate in the mechanism of disorders such as cardiac infarct, stroke, deafness, skin disea...
שמור ב:
| הוצא לאור ב: | ACS Med Chem Lett |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2018
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6047172/ https://ncbi.nlm.nih.gov/pubmed/30034603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00158 |
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