Hydrangenol inhibits the proliferation, migration, and invasion of EJ bladder cancer cells via p21(WAF1)-mediated G1-phase cell cycle arrest, p38 MAPK activation, and reduction in Sp-1-induced MMP-9 expression

Hydrangenol is a dihydroisocoumarin that is mainly obtained from Hydrangea macrophylla. Recently, hydrangenol has garnered attention since several studies have reported that it has anti-inflammatory, anti-allergic, anti-diabetic, and anti-malarial activities. However, there have been few studies on...

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Vydáno v:EXCLI J
Hlavní autoři: Shin, Seung-Shick, Ko, Myeong-Cheol, Park, Yu-Jin, Hwang, Byungdoo, Park, Sung Lyea, Kim, Wun-Jae, Moon, Sung-Kwon
Médium: Artigo
Jazyk:Inglês
Vydáno: Leibniz Research Centre for Working Environment and Human Factors 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046626/
https://ncbi.nlm.nih.gov/pubmed/30034317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2018-1361
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