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Cyclic nucleotide‐dependent inhibitory signaling interweaves with activating pathways to determine platelet responses

Platelets are regulated by extracellular cues that impact on intracellular signaling. The endothelium releases prostacyclin and nitric oxide which stimulate the synthesis of cyclic nucleotides cAMP and cGMP leading to platelet inhibition. Other inhibitory mechanisms involve immunoreceptor tyrosine‐b...

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Vydáno v:Res Pract Thromb Haemost
Hlavní autoři: Nagy, Zoltan, Smolenski, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046581/
https://ncbi.nlm.nih.gov/pubmed/30046761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12122
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