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Cyclic nucleotide‐dependent inhibitory signaling interweaves with activating pathways to determine platelet responses

Platelets are regulated by extracellular cues that impact on intracellular signaling. The endothelium releases prostacyclin and nitric oxide which stimulate the synthesis of cyclic nucleotides cAMP and cGMP leading to platelet inhibition. Other inhibitory mechanisms involve immunoreceptor tyrosine‐b...

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Bibliografske podrobnosti
izdano v:Res Pract Thromb Haemost
Main Authors: Nagy, Zoltan, Smolenski, Albert
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046581/
https://ncbi.nlm.nih.gov/pubmed/30046761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12122
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