Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition

Mast cells play an effector role in innate immunity, allergy, and inflammation. Antigen-mediated activation of mast cells initiates signaling events leading to Ca(2+) response and the release of inflammatory and allergic mediators from granules. Diseases associated with deregulated mast cell functio...

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Vydáno v:Front Immunol
Hlavní autoři: Rubíková, Zuzana, Sulimenko, Vadym, Paulenda, Tomáš, Dráber, Pavel
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046399/
https://ncbi.nlm.nih.gov/pubmed/30038620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01563
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