Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain

Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implica...

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Publicat a:Neural Plast
Autors principals: Villela, Darine, Suemoto, Claudia K., Leite, Renata, Pasqualucci, Carlos Augusto, Grinberg, Lea T., Pearson, Peter, Rosenberg, Carla
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046114/
https://ncbi.nlm.nih.gov/pubmed/30050570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2406170
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